diff --git a/packages/next/src/build/utils.ts b/packages/next/src/build/utils.ts
index 16b7dd57fa..11cb72b26b 100644
--- a/packages/next/src/build/utils.ts
+++ b/packages/next/src/build/utils.ts
@@ -20,6 +20,7 @@ import type { StaticGenerationAsyncStorage } from '../client/components/static-g
 import '../server/require-hook'
 import '../server/node-polyfill-fetch'
 import '../server/node-polyfill-crypto'
+import '../server/node-environment'
 import chalk from 'next/dist/compiled/chalk'
 import getGzipSize from 'next/dist/compiled/gzip-size'
 import textTable from 'next/dist/compiled/text-table'
@@ -62,7 +63,6 @@ import { StaticGenerationAsyncStorageWrapper } from '../server/async-storage/sta
 import { IncrementalCache } from '../server/lib/incremental-cache'
 import { patchFetch } from '../server/lib/patch-fetch'
 import { nodeFs } from '../server/lib/node-fs-methods'
-import '../server/node-environment'
 import * as ciEnvironment from '../telemetry/ci-info'
 
 export type ROUTER_TYPE = 'pages' | 'app'
diff --git a/packages/next/src/server/lib/patch-fetch.ts b/packages/next/src/server/lib/patch-fetch.ts
index bb39bf9596..4b9040e2ae 100644
--- a/packages/next/src/server/lib/patch-fetch.ts
+++ b/packages/next/src/server/lib/patch-fetch.ts
@@ -73,10 +73,14 @@ export function patchFetch({
   serverHooks: typeof ServerHooks
   staticGenerationAsyncStorage: StaticGenerationAsyncStorage
 }) {
+  if (!(globalThis as any)._nextOriginalFetch) {
+    ;(globalThis as any)._nextOriginalFetch = globalThis.fetch
+  }
+
   if ((globalThis.fetch as any).__nextPatched) return
 
   const { DynamicServerError } = serverHooks
-  const originFetch = globalThis.fetch
+  const originFetch: typeof fetch = (globalThis as any)._nextOriginalFetch
 
   globalThis.fetch = async (
     input: RequestInfo | URL,
@@ -527,8 +531,8 @@ export function patchFetch({
       }
     )
   }
-  ;(fetch as any).__nextGetStaticStore = () => {
+  ;(globalThis.fetch as any).__nextGetStaticStore = () => {
     return staticGenerationAsyncStorage
   }
-  ;(fetch as any).__nextPatched = true
+  ;(globalThis.fetch as any).__nextPatched = true
 }
diff --git a/packages/next/src/server/node-polyfill-fetch.ts b/packages/next/src/server/node-polyfill-fetch.ts
index 4e2c7006b9..1ae59a43e2 100644
--- a/packages/next/src/server/node-polyfill-fetch.ts
+++ b/packages/next/src/server/node-polyfill-fetch.ts
@@ -1,7 +1,7 @@
 // TODO: Remove use of `any` type.
 // Polyfill fetch() in the Node.js environment
 
-if (!(global as any).fetch) {
+if (typeof fetch === 'undefined' && typeof globalThis.fetch === 'undefined') {
   function getFetchImpl() {
     return require('next/dist/compiled/undici')
   }
@@ -17,7 +17,7 @@ if (!(global as any).fetch) {
   }
 
   // Due to limitation of global configuration, we have to do this resolution at runtime
-  ;(global as any).fetch = (...args: any[]) => {
+  globalThis.fetch = (...args: any[]) => {
     const fetchImpl = getFetchImpl()
 
     // Undici does not support the `keepAlive` option,
diff --git a/test/e2e/app-dir/app-static/app-static.test.ts b/test/e2e/app-dir/app-static/app-static.test.ts
index 7bfb74d7d1..8c3431c2f8 100644
--- a/test/e2e/app-dir/app-static/app-static.test.ts
+++ b/test/e2e/app-dir/app-static/app-static.test.ts
@@ -35,6 +35,36 @@ createNextDescribe(
       }
     })
 
+    it.each([
+      {
+        path: '/react-fetch-deduping-node',
+      },
+      {
+        path: '/react-fetch-deduping-edge',
+      },
+    ])(
+      'should correctly de-dupe fetch without next cache $path',
+      async ({ path }) => {
+        for (let i = 0; i < 5; i++) {
+          const res = await next.fetch(path, {
+            redirect: 'manual',
+          })
+
+          expect(res.status).toBe(200)
+          const html = await res.text()
+          const $ = cheerio.load(html)
+
+          const data1 = $('#data-1').text()
+          const data2 = $('#data-2').text()
+
+          expect(data1).toBeTruthy()
+          expect(data1).toBe(data2)
+
+          await waitFor(250)
+        }
+      }
+    )
+
     it.each([
       { pathname: '/unstable-cache-node' },
       { pathname: '/unstable-cache-edge' },
@@ -506,6 +536,8 @@ createNextDescribe(
           'partial-gen-params-no-additional-slug/fr/second.html',
           'partial-gen-params-no-additional-slug/fr/second.rsc',
           'partial-gen-params/[lang]/[slug]/page.js',
+          'react-fetch-deduping-edge/page.js',
+          'react-fetch-deduping-node/page.js',
           'route-handler-edge/revalidate-360/route.js',
           'route-handler/post/route.js',
           'route-handler/revalidate-360-isr/route.js',
diff --git a/test/e2e/app-dir/app-static/app/react-fetch-deduping-edge/page.js b/test/e2e/app-dir/app-static/app/react-fetch-deduping-edge/page.js
new file mode 100644
index 0000000000..a3b5baae04
--- /dev/null
+++ b/test/e2e/app-dir/app-static/app/react-fetch-deduping-edge/page.js
@@ -0,0 +1,29 @@
+export const runtime = 'edge'
+
+export default async function Page() {
+  const data1 = await fetch(
+    'https://next-data-api-endpoint.vercel.app/api/random?1',
+    {
+      next: {
+        revalidate: 0,
+      },
+    }
+  ).then((res) => res.text())
+
+  const data2 = await fetch(
+    'https://next-data-api-endpoint.vercel.app/api/random?1',
+    {
+      next: {
+        revalidate: 0,
+      },
+    }
+  ).then((res) => res.text())
+
+  return (
+    <>
+      <p>/react-fetch-deduping</p>
+      <p id="data-1">{data1}</p>
+      <p id="data-2">{data2}</p>
+    </>
+  )
+}
diff --git a/test/e2e/app-dir/app-static/app/react-fetch-deduping-node/page.js b/test/e2e/app-dir/app-static/app/react-fetch-deduping-node/page.js
new file mode 100644
index 0000000000..3b7a3df3ca
--- /dev/null
+++ b/test/e2e/app-dir/app-static/app/react-fetch-deduping-node/page.js
@@ -0,0 +1,27 @@
+export default async function Page() {
+  const data1 = await fetch(
+    'https://next-data-api-endpoint.vercel.app/api/random?1',
+    {
+      next: {
+        revalidate: 0,
+      },
+    }
+  ).then((res) => res.text())
+
+  const data2 = await fetch(
+    'https://next-data-api-endpoint.vercel.app/api/random?1',
+    {
+      next: {
+        revalidate: 0,
+      },
+    }
+  ).then((res) => res.text())
+
+  return (
+    <>
+      <p>/react-fetch-deduping</p>
+      <p id="data-1">{data1}</p>
+      <p id="data-2">{data2}</p>
+    </>
+  )
+}